Sherry Stringfield

In a surprising twist, ER producer John Wells shared how Noah Wyle snagged his role in the acclaimed medical series. Initially, the part was already cast, but the then-22-year-old waiter caught Wells' eye with his innovative audition performances, bringing fresh perspectives that ultimately led to his last-minute inclusion in the show, where he quickly became a fan favorite.

Julianna Margulies, known for her role as Carol Hathaway on 'ER,' recently shared the surprising story behind her casting. Initially auditioning for a different role, she impressed the casting director with her 'New York rage' and landed the part of Carol, a character originally intended to die in the pilot episode.

George Clooney led a parade of old favorites back to ``ER’ as the medical drama nears the end of its 15-year run.