The 2025 NFL season kicks off in historic fashion tonight as the Kansas City Chiefs face the Los Angeles Chargers at Arena Corinthians in São Paulo, Brazil. It’s a landmark game in the league’s global expansion efforts – but much of the spotlight is focused on Chargers running back Najee Harris, who is set to make his return after a bizarre offseason injury.
Harris missed the entirety of training camp and the preseason following a July 4 fireworks mishap that caused a minor eye injury and landed him on the Non-Football Injury (NFI) list. That led to questions about whether he’d be ready for Week 1 or not.
Will Najee Harris play tonight against the Kansas City Chiefs? (September 5)
Yes, Najee Harris will be active and in uniform for tonight’s international season opener. The 26-year-old was officially added back to the Chargers' 53-man roster earlier this week and was removed from the injury report after fully participating in practices. Head coach Jim Harbaugh confirmed Harris is “good to go”.
However, Harris is not expected to start. Rookie Omarion Hampton is projected to handle the opening carries, while Harris eases back into game action after missing extended preseason work. Even in a rotational role, Harris brings valuable experience to the Chargers' offense as they take on a Chiefs defense that will look to contain the run.
Kansas City Chiefs vs. Los Angeles Chargers game details and how to watch
- Date: Friday, Sept. 5, 2025
- Time: 8:00 p.m. ET (7:00 p.m. CT)
- Venue: Arena Corinthians, São Paulo, Brazil
- TV/Stream: YouTube (free), NFL+
- Local Broadcasts: KSHB 41 (Kansas City), KNBC (Los Angeles)
Najee Harris brings veteran presence to revamped offense
While Harris may not be the featured back tonight, his return marks a key step for a Chargers offense undergoing transition under new head coach Jim Harbaugh. The former first-round pick offers stability, pass protection, and veteran savvy – all of which will be important as the team breaks in a new-look backfield. With Patrick Mahomes and
Travis Kelce leading the opposing sideline, the Chargers know they’ll need to match firepower with balance and ball control. Whether he’s starting or spelling Hampton, Harris will be a key factor in helping L.A. find that rhythm.
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Patriots Super Bowl champion Jamie Collins and wife Kat Tat list their Florida mansion for $4 million, blending legacy with celebrity luxuryAfter a chaotic offseason, the focus now turns to the field – and Harris has a chance to make an immediate impact in a game watched around the world.