Philadelphia 76ers vs Cleveland Cavaliers (01-16-2026) game preview: When and where to watch, expected lineup, injury report, prediction, and more

Cleveland covered as a 1-point away underdog with the Over (236.5) paying and easily defeated Philadelphia 133-107 on Wednesday. In the victory, the Cavaliers made 20 of 46 (43%) long-range shots while the Sixers only made 12 of 43 (28%).

In the season's opening game on November 5, the Cavaliers defeated the Sixers 132-121, although Philly covered as a 16.5-point away underdog and the Over (235.5) hit. The Cavaliers have led in paint points and fast-break points in both games this season and have shot more than 40% from beyond the arc.

Philadelphia 76ers vs Cleveland Cavaliers - When and where to watch the game

On Friday, the Philadelphia 76ers (22-17) and Cleveland Cavaliers (23-19) will square off for the second time in three nights. The tip-off from Philadelphia's Xfinity Mobile Arena is scheduled for 7 p.m. ET (ESPN). ESPN and FanDuel Sports Network - Ohio will telecast the entire match. Additionally, Fubo and Prime Videos will stream the match for online users.

Philadelphia 76ers vs Cleveland Cavaliers - Expected Starting Lineups

Philadelphia 76ers

PG Tyrese Maxey
SG VJ Edgecombe
SF Paul George
PF Dominick Barlow
C Joel Embiid

Cleveland Cavaliers

PG Craig Porter Jr.
SG Donovan Mitchell
SF Jaylon Tyson
PF Evan Mobley
C Jarrett Allen

Philadelphia 76ers vs Cleveland Cavaliers - Injury Report

Philadelphia 76ers

• Dominick Barlow- Day-to-day (Unspecified reason)
• Paul George- Day-to-day (Left knee injury management)
• Joel Embiid- Day-to-day (Left knee injury management)

Cleveland Cavaliers

• Dean Wade- Out (Knee)
• Sam Merrill- Out (Right hand sprain)
• Darius Garland- Out (Foot)
• Max Strus- Out (Foot)
• Chris Livingston- Out (A two-way contract)

Philadelphia 76ers vs Cleveland Cavaliers - Game Prediction

The Cleveland Cavaliers visit the Philadelphia 76ers for their second game in three days, kicking up the Friday NBA schedule with an Eastern Conference duel. When these teams faced in Philadelphia on Wednesday, Cleveland prevailed 133-107. The Sixers are 22-17 this season, while the Cavaliers are 23-19. However, Philadelphia has outperformed the market, going 23-15 against the spread, while Cleveland is only 14-28 ATS.

The 76ers have scored more than 234.5 points in 16 of their 39 games this season, which is their current matchup's over/under. The Cavaliers have scored more than 234.5 points in 22 of their 42 games this season. Together, these two teams score 236.9 points per game on average, which is 2.4 higher than the 234.5 points allotted for this game.


Also read: Philadelphia 76ers vs Brooklyn Nets (12-23-2025) game preview: When and where to watch, expected lineup, injury report, prediction, and more



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